Article

High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study

2021-03-17

Abstract excerpt

<h4>Background</h4> There is on-going controversy regarding the potential for increased respiratory effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing patients with COVID-19 acute hypoxaemic respiratory failure. However, direct clinical evidence linking increased inspiratory effort to lung injury is scarce. We adapted a computational simulator of cardiopulmonary pathophysiolo...

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Literature Corpus work: 26517c45-b756-5598-a253-6ed6979426cb
DOI: 10.1101/2021.03.17.21253788

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