Article
Phenotypes based on respiratory drive and effort to identify the risk factors when P0.1 fails to estimate ∆PES in ventilated children.
Critical care (London, England) - 4 Oct 2024
Vedrenne-Cloquet Meryl, Ito Y, Hotz J, Klein M J, Herrera M, Chang D, Bhalla A K, Newth C J L, Khemani R G
Abstract excerpt
BACKGROUND: Monitoring respiratory effort and drive during mechanical ventilation is needed to deliver lung and diaphragm protection. Esophageal pressure (∆PES) is the gold standard measure of respiratory effort but is not routinely available. Airway occlusion pressure in the first 100 ms of the breath (P0.1) is a readily available surrogate for both respiratory effort and drive but is only modestly correlated...
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