Back to search

Article

Metagenomic NGS and Targeted NGS Driven Precision Therapy in Pediatric Chemotherapy-Associated Infections: A Single-Center Retrospective Study

2026-01-13

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Infections in immunocompromised pediatric hematology-oncology patients present a major challenge. This study utilized pathogen NGS (metagenomic next generation sequencing (mNGS) / targeted next generation sequencing (tNGS)) to characterize the microbial spectrum in this population, thereby enhancing detection and enabling targeted antimicrobial therapy. <bold...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
750ab890-f55e-5112-af2f-4c2fa651519f
DOI
10.21203/rs.3.rs-8485427/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Metagenomic NGS and Targeted NGS Driven Precision Therapy in Pediatric Chemotherapy-Associated Infections: A Single-Center Retrospective StudyDOI 10.21203/rs.3.rs-8485427/v1
Clinical Assessment of the Utility of Metagenomic Next-Generation Sequencing in Pediatric Patients of Hematology DepartmentSemantic proximity
Comparison of plasma and blood cell samples in metagenomic next-generation sequencing for identification of the causative pathogens of feverSemantic proximity
Utility of Metagenomic Next-Generation Sequencing for Diagnosis of Infectious Diseases in Critically Ill Immunocompromised Pediatric PatientsSemantic proximity
Sequence-based diagnostics and precision medicine in bacterial and viral infections: from bench to bedsideSemantic proximity
Enhanced Pathogen Detection in Hematology Patients with Respiratory Infections Using Targeted Next-Generation Sequencing (tNGS)Semantic proximity
Metagenomic Next-Generation Sequencing In Febrile Neutropaenia of Children Hematological And Malignant DiseasesSemantic proximity
Metagenomic Next-Generation Sequencing for Infectious Disease Diagnosis: A Review of the Literature With a Focus on PediatricsSemantic proximity
Diagnosis of infectious diseases in immunocompromised hosts using metagenomic next generation sequencing-based diagnosticsSemantic proximity
Diagnosis of Neurological Infections in Pediatric Patients from Cell-Free DNA Specimens by Using Metagenomic Next-Generation SequencingSemantic proximity
Diagnostic Performance of Metagenomic Next-Generation Sequencing in Pediatric Patients: A Retrospective Study in a Large Children’s Medical CenterSemantic proximity
Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort StudySemantic proximity
Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort StudySemantic proximity
Select a neighboring publication to make it the new centre.