Article

LRFN5 locus structure is influenced by the individual’s sex and associated with autism

2021-09-15

Abstract excerpt

<title>Abstract</title> <p>BackgroundLRFN5 is a brain-specific gene needed for synaptic development and plasticity. It is the only gene in a large 5.4 Mb topologically associating domain (TAD) on chromosome 14, which we term the LRFN5 locus. This locus is highly conserved, but has extensive copy number variation. MethodsLocus structure was studied by chromatin immunoprecipitation (chIP-onchip) in fibroblasts from...

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Literature Corpus work: 743a5132-01d3-5472-a827-1db6a7715dac
DOI: 10.21203/rs.3.rs-895724/v1

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