Article
High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
Molecular psychiatry - 1 Sept 2010
Maestrini E, Pagnamenta A T, Lamb J A, Bacchelli E, Sykes N H, Sousa I, Toma C, Barnby G, Butler H, Winchester L, Scerri T S, Minopoli F, Reichert J, Cai G, Buxbaum J D, Korvatska O, Schellenberg G D, Dawson G, de Bildt A, Minderaa R B, Mulder E J, Morris A P, Bailey A J, Monaco A P
Abstract excerpt
Autism spectrum disorders are a group of highly heritable neurodevelopmental disorders with a complex genetic etiology. The International Molecular Genetic Study of Autism Consortium previously identified linkage loci on chromosomes 7 and 2, termed AUTS1 and AUTS5, respectively. In this study, we performed a high-density association analysis in AUTS1 and AUTS5, testing more than 3000 single nucleotide...
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