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A Primeval Mechanism of Tolerance to Desiccation Based on Glycolic Acid Saves Neurons from Ischemia in Mammals by Reducing Intracellular Calcium-Mediated Excitotoxicity

2020-11-24

Abstract excerpt

<h4>ABSTRACT</h4> Stroke is the second leading cause of death and disability worldwide. Current treatments, such as pharmacological thrombolysis or mechanical thrombectomy, re-open occluded arteries but do not protect against ischemia-induced damage that has already occurred before reperfusion or ischemia/reperfusion-induced neuronal damage. It has been shown that disrupting the conversion of glyoxal to glycolic...

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Literature Corpus work: 73e9713c-5984-5ca9-bc18-17f94ec7aedd
DOI: 10.1101/2020.11.24.396051

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