Article

Mesothelioma location influences the tumour microenvironment and immune checkpoint therapy response in preclinical models

2025-12-22

Abstract excerpt

<title>Abstract</title> <p>Mesothelioma is a cancer derived from mesothelial cells, most commonly arising from the pleura or the peritoneum. Immune checkpoint therapy (ICT) has shown survival benefit for pleural mesothelioma, but little is known about the response in peritoneal mesothelioma. Most preclinical mesothelioma models involve subcutaneous cancer cell implantation, which lacks the relevant tumour microen...

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Literature Corpus work: 73918bc1-06f6-514a-b4e9-02e4123e391c
DOI: 10.21203/rs.3.rs-8016867/v1

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