Article

Comparative Analysis of Manual and Automated (HbA1c) Methods in β-Thalassemia Carriers with Diabetes

2026-01-20

Abstract excerpt

<h4>Background: </h4> Hemoglobin A1c is widely recognized as an indicator of long-term glucose control in patients with diabetes. Its measurement, however, can be influenced by several hemoglobin disorders, including the β-thalassemia trait, which is relatively common in the Middle East. Methods This work compared manual HbA1c testing procedures with an automated high-performance liquid chromatography (HPLC) techn...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7385efa4-b6df-5836-b3cf-3b89a51d145e
DOI: 10.12688/f1000research.174502.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative Analysis of Manual and Automated (HbA1c) Methods in β-Thalassemia Carriers with DiabetesDOI 10.12688/f1000research.174502.1Read

Prevalence of hemoglobin variants in a diabetic population at high risk of hemoglobinopathies and optimization of HbA1c monitoring by incorporating HPLC in the laboratory workup.Semantic proximity Read

Haemoglobin types and variant interference with HbA1c and its association with uncontrolled HbA1c in type 2 diabetes mellitusSemantic proximity Read

Haemoglobin variants may cause significant differences in haemoglobin A1c as measured by high-performance liquid chromatography and enzymatic methods in diabetic patients: a cross-sectional study.Semantic proximity Read

[Influence and analysis of seven kinds of hemoglobin variants on HbA1c detection].Semantic proximity Read

Hb variants in Korea: effect on HbA1c using five routine methods.Semantic proximity Read

Prediction the Occurrence of Thalassemia With Hematological Phenotype by Diagnosis of Abnormal HbA1c.Semantic proximity Read

Interference of hemoglobinA1c (HbA1c) detection using ion-exchange high performance liquid chromatography (HPLC) method by clinically silent hemoglobin variant in University Malaya Medical Centre (UMMC)--a case report.Semantic proximity Read

Effects of the Hb E, Hb H and Hb G-Taichung variants on HbA1c values by the Bio-Rad variant II turbo analyzer.Semantic proximity Read

Hemoglobin A2 (HbA2) has a measure of unreliability in diagnosing β-thalassemia trait (β-TT).Semantic proximity Read

Eleven Cases of Hb J-Paris-I [HBA2: c.38C>A (or HBA1)]: A Stable α Chain Variant Elutes in the P3 Window on High-Performance Liquid Chromatography.Semantic proximity Read

Evaluation of role of HPLC (Merits & Pitfalls), in the diagnosis of various hemoglobinopathies & thalassemic syndromes.Semantic proximity Read

[Importance of the characteristics of the chromatographic separation in HPLC for the interpretation of HbA1c assay in the presence of a variant hemoglobin].Semantic proximity Read