Article
[Importance of the characteristics of the chromatographic separation in HPLC for the interpretation of HbA1c assay in the presence of a variant hemoglobin].
Annales de biologie clinique - 1 Jan 2000
Guillard Emmanuelle, Jaisson Stéphane, Gillery Philippe
Abstract excerpt
The methods of HbA1c assay using ion exchange high pressure liquid chromatography (HPLC) allow the detection of the most common hemoglobin variants. This observation highlights the different behaviour of two HPLC analyzers in the presence of Tatras hemoglobin. By one of the analyzer (Variant II, Bio-Rad) this variant is detected, but not by the other (G8, Tosoh Biosciences). As HbA1c result is crucial for the...
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