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Splicing Factor SF3B2 Regulates Cardiomyocyte Calcium Handling Through Alternative Splicing of Cardiac Ion Channel Genes

2026-07-28

Abstract excerpt

<h4>Background</h4> Alternative splicing is a critical determinant of protein diversity in the heart, where it drives the postnatal functional maturation of cardiomyocytes and specifies the ion-channel and calcium-handling isoforms required for mature contractile function; dysregulated splicing programs have in turn been implicated in cardiomyopathies and arrhythmias. However, the splicing regulators that control...

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Literature Corpus work
733caf3e-d410-5c13-8601-aa70526417ac
DOI
10.64898/2026.07.25.740735
Open publication

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Splicing Factor SF3B2 Regulates Cardiomyocyte Calcium Handling Through Alternative Splicing of Cardiac Ion Channel GenesDOI 10.64898/2026.07.25.740735
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