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Erythropoietin alleviates intellectual disability and autism-like behavior of mice caused by <i>Zbtb20</i> haploinsufficiency, a construct-valid model of Primrose syndrome

2025-09-13

Abstract excerpt

Among the known genetic causes of syndromic autism spectrum disorders (ASD) are transcription factor deficiencies. In this regard, haploinsufficiency of the ‘zinc finger and broad complex, tramtrack, bric and brac domain-containing protein 20’ (ZBTB20) leads to a prototypical clinical picture, referred to as Primrose syndrome, comprising severe ASD symptoms together with intellectual disability. Here, we present...

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Literature Corpus work
732a05fa-dfeb-5a67-9127-490b3c8ecaec
DOI
10.1101/2025.09.11.675680
Open publication

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Erythropoietin alleviates intellectual disability and autism-like behavior of mice caused by <i>Zbtb20</i> haploinsufficiency, a construct-valid model of Primrose syndromeDOI 10.1101/2025.09.11.675680
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