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A genomic perspective on the near-term impact of doxycycline post-exposure prophylaxis on <i>Neisseria gonorrhoeae</i> antimicrobial resistance

2023-03-17

Abstract excerpt

Post-exposure prophylaxis with doxycycline (doxyPEP) is being introduced to prevent bacterial sexually transmitted infections (STIs). Pre-existing tetracycline resistance in Neisseria gonorrhoeae limits doxyPEP effectiveness against gonorrhea, and selection for tetracycline resistant lineages may influence prevalence of resistance to other antimicrobials via selection for multi-drug resistant strains. Using genom...

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Identifiers and source

Literature Corpus work
72ead119-053c-589e-a1c4-94a658bcd92f
DOI
10.1101/2023.03.14.23287223
Open publication

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