Back to search

Article

Unlocking uterine biology at home: a validated system for DNA, RNA, and microbial analysis from menstrual effluence

2025-05-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Access to accurate, non-invasive diagnostics remains a critical unmet need in women’s health. Menstrual effluence, containing endometrial tissue, immune cells, and microbial communities, represents a clinically relevant specimen for genomic and molecular pathology applications, yet has historically been underutilized due to concerns about sample integrity and variability. <h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
72917f69-09ee-57a7-b7d2-2cd7e83f37da
DOI
10.1101/2025.05.21.25327630
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Unlocking uterine biology at home: a validated system for DNA, RNA, and microbial analysis from menstrual effluenceDOI 10.1101/2025.05.21.25327630
Menstrual Blood as a Diagnostic Specimen for Human Papillomavirus Genotyping and Genital Tract Infection Using Next-Generation Sequencing as a Novel Diagnostic ToolSemantic proximity
Evaluating sequencing strategies for endometrial microbiome profiling in endometrial cancer: a comparative study of short- and long-read 16S rRNA approachesSemantic proximity
The microbiota continuum along the female reproductive tract and its relation to uterine-related diseasesSemantic proximity
The Female Reproductive Tract Microbiome—Implications for Gynecologic Cancers and Personalized MedicineSemantic proximity
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA SequencingSemantic proximity
The Registry of Pregnant Women at Cruces University Hospital: an ethical framework for prospective research with preanalytical optimization of maternal plasma processingSemantic proximity
RNA/DNA co-analysis from human menstrual blood and vaginal secretion stains: Results of a fourth and fifth collaborative EDNAP exerciseSemantic proximity
Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive HealthSemantic proximity
Quantifying inflammatory resolution in human menstruation reveals disease-specific failure modes and enables a non-invasive diagnostic for endometriosisSemantic proximity
Single cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosisSemantic proximity
Optimizing single-cell RNA sequencing methods for human colon biopsies: droplet-based vs. picowell-based platformsSemantic proximity
Re‐assessing microbiomes in the low‐biomass reproductive nicheSemantic proximity
Select a neighboring publication to make it the new centre.