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FSCN1 Modulates Tumor Growth and Innate Immune Pathways through Synergistic Interaction with PIK3CA Mutations

2025-06-26

Abstract excerpt

<title>Abstract</title> <p>Background Tumor-specific genetic alterations critically drive cancer progression and therapeutic resistance through both cell- and non-cell-autonomous mechanisms. While the actin-binding protein FSCN1 has been linked to tumor progression, its role in shaping immune evasion and tumor growth in PIK3CA-mutant cancers remains poorly understood. This study investigated the mechanism by whi...

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Literature Corpus work
71a7af1b-4cd8-5283-9aee-26da6f243414
DOI
10.21203/rs.3.rs-6662400/v1
Open publication

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FSCN1 Modulates Tumor Growth and Innate Immune Pathways through Synergistic Interaction with PIK3CA MutationsDOI 10.21203/rs.3.rs-6662400/v1
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