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Identifying the oncogenic roles of FAP in human cancers based on systematic analysis

24 Jul 2023

Abstract excerpt

BACKGROUND: Fibroblast activation protein-α (FAP) is a specific marker of cancer-associated fibroblasts (CAFs) and plays a crucial role in tumor development. However, the biological processes underlying FAP expression in tumor progression and tumor immunity have not been fully elucidated. METHODS: We utilized RNA-seq data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) to perform...

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PMID: 37490719
DOI: 10.18632/aging.204892

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