Article

Silencing of SARS-CoV-2 with modified siRNA-peptide dendrimer formulation

2021-02-17

Abstract excerpt

<h4>Background: </h4> First vaccines for prevention of Coronavirus disease 2019 (COVID-19) are becoming available but there is a huge and unmet need for specific forms of treatment. In this study we aimed to evaluate the potent anti-SARS-CoV-2 effect of siRNA both in vitro and in vivo. Methods. To identify most effective molecule out of a panel of 15 in silico designed siRNAs, an in vitro screening system based on...

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Literature Corpus work: 719e0a8e-14ab-5ccd-a37f-582dbae54f22
DOI: 10.22541/au.161359798.81563481/v1

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