Article

Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection

2023-09-07

Abstract excerpt

<h4>ABSTRACT</h4> A first line of defense during infection is expression of interferon (IFN)-stimulated gene products which suppress viral lytic infection. To combat this, herpesviruses express endoribonucleases to deplete host RNAs. Here we demonstrate that IFN-induced circular RNAs (circRNAs) can escape viral-mediated degradation. We performed comparative circRNA expression profiling for representative alpha- (...

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Literature Corpus work: 71986220-8f7d-5c3b-a1a7-bcbecfb6ca6e
DOI: 10.1101/2023.09.07.556698

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