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Suberoylanilide Hydroxamic Acid (SAHA) Treatment Reveals Crosstalk Among Proteome, Phosphorylome and Acetylome in Nasopharyngeal Carcinoma Cells

2021-07-20

Abstract excerpt

<title>Abstract</title> <p>Suberoylanilide hydroxamic acid (SAHA), as a famous histone deacetylase (HDAC) inhibitor, has been utilized in clinical treatment for cutaneous T-cell lymphoma. Previously the mechanisms underlying SAHA anti-tumor mainly focused on acetylome. However, the characteristics of SAHA in terms of other protein posttranslational modifications (PTMs) and the crosstalk between various modificati...

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Literature Corpus work
718f77f7-fb90-5162-ae3a-e36b39569b04
DOI
10.21203/rs.3.rs-655483/v1
Open publication

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Suberoylanilide Hydroxamic Acid (SAHA) Treatment Reveals Crosstalk Among Proteome, Phosphorylome and Acetylome in Nasopharyngeal Carcinoma CellsDOI 10.21203/rs.3.rs-655483/v1
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