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Genomic 8-oxoguanine is associated with transcriptionally active chromatin and elevated gene expression in <i>Plasmodium falciparum</i>

2026-06-25

Abstract excerpt

Epigenetic regulation is central to the developmental progression and pathogenicity of the unicellular eukaryotic parasite Plasmodium falciparum ; yet, the contribution of DNA base modifications remains poorly understood. One such modification, 8-oxoguanine (8-oxoG), which was initially identified as an oxidative lesion and a marker of DNA damage, has since emerged as a transcriptional regulator in advanced eukar...

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Literature Corpus work
7177d27d-6dea-531c-b542-c0e52e592c3b
DOI
10.64898/2026.06.21.733641
Open publication

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Genomic 8-oxoguanine is associated with transcriptionally active chromatin and elevated gene expression in <i>Plasmodium falciparum</i>DOI 10.64898/2026.06.21.733641
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