Article

Mitochondrial transplantation improves bioenergetics and neurite outgrowth in disease-associated P301Ltau-expressing neuronal cells

2025-05-02

Abstract excerpt

<title>Abstract</title> <p>Tauopathies are neurodegenerative diseases characterized by the abnormal accumulation of tau protein in neurons, leading to cognitive impairment. A common feature of these disorders is mitochondrial dysfunction, which results in bioenergetic deficits and contributes to neuronal death. As neurons have high energy demands, impaired mitochondrial function directly affects their viability a...

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Literature Corpus work: 715e07f1-c37f-5c8f-8b56-71d8cd31fe30
DOI: 10.21203/rs.3.rs-6502413/v1

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