Article
Exploring the potential mechanism of Polygonatum sibiricum for Alzheimer's disease based on network pharmacology and molecular docking
2024-04-17
Abstract excerpt
Alzheimer's disease (AD) is a neurodegenerative disease, and there have been no systematic studies of Polygonatum against Alzheimer's disease. This study aimed to identify the primary active components and potential mechanisms of action of Polygonatum in the treatment of AD through network pharmacology and molecular docking. Polygonatum's active ingredients and corresponding targets were identified using the Tradi...
Topics
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- Alzheimer's disease research and treatments
- Berberine and alkaloids research
- Cholinesterase and Neurodegenerative Diseases
- Computational Drug Discovery Methods
- Curcumin's Biomedical Applications
- Ginseng Biological Effects and Applications
- Metabolomics and Mass Spectrometry Studies
- Paraoxonase enzyme and polymorphisms
Identifiers and source
- Literature Corpus work
- 96b64081-605e-5782-aaad-2d49ade39f22
- DOI
- 10.21203/rs.3.rs-4225413/v1
