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Resveratrol activates MAPK/ERK pathway to regulate oestrogen metabolism in type I endometrial cancer

11 Jun 2024

Abstract excerpt

OBJECTIVE: Endometrial cancer (EC) is an oestrogen-dependent tumour, the occurrence of which is closely related to an imbalance of oestrogen homeostasis. Our previous studies explored the effects of Resveratrol(Res) on oestrogen metabolism. However, systematic research on the exact mechanism of action of Res is still lacking. Based on network pharmacology, molecular docking and animal experiments, the effects and...

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PMID: 38862934
DOI: 10.1186/s12906-024-04509-y

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