Article

Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer and coronary disease pathways

2022-07-25

Abstract excerpt

Identification of the plasma proteomic changes of Coronavirus disease 2019 (COVID-19) is essential to understanding the pathophysiology of the disease and developing predictive models and novel therapeutics. We performed plasma deep proteomic profiling from 332 COVID-19 patients and 150 controls and pursued replication in an independent cohort (297 cases and 76 controls) to find potential biomarkers and causal pro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 70a7400b-18c8-5348-9b53-5551abf3d2b0
DOI: 10.1101/2022.07.25.22278025

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer and coronary disease pathwaysDOI 10.1101/2022.07.25.22278025Read

Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer’s and coronary disease pathwaysSemantic proximity Read

Plasma proteomics identify potential severity biomarkers from COVID‐19 associated networkSemantic proximity Read

Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patientsSemantic proximity Read

Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19.Semantic proximity Read

Studying the pathophysiology of coronavirus disease 2019 – a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19)Semantic proximity Read

Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19Semantic proximity Read

Proteomics Analysis of Serum from COVID-19 PatientsSemantic proximity Read

Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19).Semantic proximity Read

Analysis of inflammatory protein profiles in the circulation of COVID-19 patients identifies patients with severe disease phenotypes.Semantic proximity Read

Shared genetics and causal association between plasma levels of SARS-CoV-2 entry receptor ACE2 and Alzheimer's disease.Semantic proximity Read

Plasma Proteomic Variables Related to COVID-19 Severity: An Untargeted nLC-MS/MS InvestigationSemantic proximity Read

Mapping the Serum Proteome of COVID-19 Patients; Guidance for Severity AssessmentSemantic proximity Read