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Article

Contribution of the caspase gene sequence diversification to the specifically antiviral defense in invertebrate.

PloS one - 1 Jan 2011

Zhi Bin, Wang Lei, Wang Guangyi, Zhang Xiaobo

Abstract excerpt

Vertebrates achieve adaptive immunity of all sorts against pathogens through the diversification of antibodies. However the mechanism of invertebrates' innate immune defense against various pathogens remains largely unknown. Our study used shrimp and white spot syndrome virus (WSSV) to show that PjCaspase, a caspase gene of shrimp that is crucial in apoptosis, possessed gene sequence diversity. At present, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21949804
DOI: 10.1371/journal.pone.0024955
PMCID: PMC3176291

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