Article

NetMix: A network-structured mixture model for reduced-bias estimation of altered subnetworks

2020-01-19

Abstract excerpt

A classic problem in computational biology is the identification of altered subnetworks: subnetworks of an interaction network that contain genes/proteins that are differentially expressed, highly mutated, or otherwise aberrant compared to other genes/proteins. Numerous methods have been developed to solve this problem under various assumptions, but the statistical properties of these methods are often unknown. F...

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Literature Corpus work: 6f9fcb69-7f6e-52a5-8480-0de3748b068f
DOI: 10.1101/2020.01.18.911438

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