Article

Transcriptomic Phases of Periodontitis Lesions Using the Nonhuman Primate Model

2021-02-10

Abstract excerpt

We used a nonhuman primate model of ligature-induced periodontitis to identify patterns of gingival transcriptomic changes demarcating phases of periodontitis lesions (initiation, progression, resolution). 18 adult Mulatta macaca (12-22 years) had ligatures placed (premolar, 1st molar teeth) in all 4 quadrants. Gingival tissue samples were obtained (baseline, 2 weeks, 1 and 3 months during periodontitis and at 5 m...

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Literature Corpus work: 6f7afb01-ce11-5b56-aa3f-a97e22ab2aa4
DOI: 10.21203/rs.3.rs-180948/v1

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