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Transcriptomic phases of periodontitis lesions using the nonhuman primate model

29 Apr 2021

Abstract excerpt

We used a nonhuman primate model of ligature-induced periodontitis to identify patterns of gingival transcriptomic after changes demarcating phases of periodontitis lesions (initiation, progression, resolution). A total of 18 adult Macaca mulatta (12-22 years) had ligatures placed (premolar, 1st molar teeth) in all 4 quadrants. Gingival tissue samples were obtained (baseline, 2 weeks, 1 and 3 months during...

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PMID: 33927312
DOI: 10.1038/s41598-021-88803-6

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