Article

American mink as an animal model to study SARS-CoV-2 and vaccine response

2025-06-11

Abstract excerpt

Selecting a suitable animal model is crucial in understanding infectious diseases and developing vaccines. Here, we developed a receptor-binding domain -based SARS-CoV-2 vaccine with mouse Fc an immunopotentiator in a mink model. Four different variations of the vaccine were tested in groups of 30-31 American mink and followed for IgG and neutralizing antibodies (nAb) up to 27 weeks. Subcutaneous version induced a...

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Literature Corpus work: 6f402e42-5f46-5a83-a670-d3c23a48b239
DOI: 10.1101/2025.06.10.658224

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