Article

Lower serum level of miRNA-21 may be considered as a comorbidity-independent characteristic of frailty in cardiovascular patients

2025-11-19

Abstract excerpt

<title>Abstract</title> <p>We examined the serum level of miRNA-21 in a cohort of frail cardiovascular patients. We have enrolled 261 patients into this ancillary analysis of the FRAPICA trial (ClinicalTrials.org NCT03209414, registered 06/07/20217). The phenotype Fried frailty scale identified 93 robust, 131 pre-frail, and 37 frail patients. The groups differed in terms of demographics, morphology, and clinical...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6f2b76d2-e6b8-53d3-aad9-52dc53a1106a
DOI: 10.21203/rs.3.rs-7133943/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lower serum level of miRNA-21 may be considered as a comorbidity-independent characteristic of frailty in cardiovascular patientsDOI 10.21203/rs.3.rs-7133943/v1Read

Exploring Frailty in the Intersection of Cardiovascular Disease and Cancer in Older PeopleSemantic proximity Read

Exploring Frailty in the Intersection of Cardiovascular Disease and Cancer in Older People.Semantic proximity Read

miRNome Profiling Detects miR-101-3p and miR-142-5p as Putative Blood Biomarkers of Frailty SyndromeSemantic proximity Read

Circulating miRNAs Associated with Frailty in Old People with Cardiovascular Diseases Promote Cellular Senescence and InflammationSemantic proximity Read

Proteomic architecture of frailty across the spectrum of cardiovascular diseaseSemantic proximity Read

Inflammatory Markers and Clinical Factors as Key Independent Risk Factors for Frailty: A Retrospective StudySemantic proximity Read

The Potential Role of miRNAs in Cognitive FrailtySemantic proximity Read

A cross-sectional survey of prevalence and related factors for frail status among middle-aged and elderly people in Chinese communitiesSemantic proximity Read

Prevalence of Frailty Syndrome in Colombian Population Aged Over 65 Scheduled for Non-Cardiac Elective SurgerySemantic proximity Read

Fibroblast Growth Factor-23 and Frailty in Elderly Community-Dwelling Individuals: The Cardiovascular Health Study.Semantic proximity Read

Association between frailty and albuminuria in the community-dwelling geriatric population: Taichung Community Health Study for EldersSemantic proximity Read

Physical frailty Is Associated with Increased Risk of Adverse Clinical Outcomes in Patients with Stable Coronary Artery DiseaseSemantic proximity Read