Article

Characterisation of the novel mechanism of protein-directed translation initiation used by caliciviruses

2012-01-01

Abstract excerpt

Human noroviruses of the Caliciviridae family are the major cause of acute gastroenteritis in the developed world, but little is known about their molecular mechanisms of translation and replication. Since human noroviruses are not cultivatable in vitro, most molecular studies have therefore been based on the cultivatable murine norovirus (MNV) or feline calicivirus from the Vesivirus genera. Calicivirus translati...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6eb63376-3c1d-5b89-b3c9-2c1aae065963
DOI: 10.25560/10556

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterisation of the novel mechanism of protein-directed translation initiation used by calicivirusesDOI 10.25560/10556Read

Protein-RNA linkage and posttranslational modifications of feline calicivirus and murine norovirus VPg proteinsSemantic proximity Read

The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment.Semantic proximity Read

Protein-RNA linkage and posttranslational modifications of feline calicivirus and murine norovirus VPg proteinsSemantic proximity Read

Sapovirus Translation Requires an Interaction between VPg and the Cap Binding Protein eIF4ESemantic proximity Read

Caliciviruses differ in their functional requirements for eIF4F components.Semantic proximity Read

Cleavage of eukaryotic initiation factor eIF4G and inhibition of host-cell protein synthesis during feline calicivirus infectionSemantic proximity Read

Studies on the mechanism of norovirus RNA synthesisSemantic proximity Read

Identification and characterisation of an overlapping open reading frame (ORF4) within the murine norovirus genomeSemantic proximity Read

Norovirus translation and replicationSemantic proximity Read

Functions of the 5′ and 3′ ends of calicivirus genomesSemantic proximity Read

Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 CleavageSemantic proximity Read

Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal calicivirusesSemantic proximity Read