Article
Caliciviruses differ in their functional requirements for eIF4F components.
The Journal of biological chemistry - 1 Sept 2006
Chaudhry Yasmin, Nayak Arabinda, Bordeleau Marie-Eve, Tanaka Junichi, Pelletier Jerry, Belsham Graham J, Roberts Lisa O, Goodfellow Ian G
Abstract excerpt
Two classes of viruses, namely members of the Potyviridae and Caliciviridae, use a novel mechanism for the initiation of protein synthesis that involves the interaction of translation initiation factors with a viral protein covalently linked to the viral RNA, known as VPg. The calicivirus VPg proteins can interact directly with the initiation factors eIF4E and eIF3. Translation initiation on feline calicivirus...
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