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Article

Cross talk between drug‐resistant epilepsy and the gut microbiome

2 Nov 2020

Abstract excerpt

One-third of epilepsy patients have drug-resistant epilepsy (DRE), which is often complicated by polydrug toxicity and psychiatric and cognitive comorbidities. Advances in understanding the microbiome and gut-brain-axis are likely to shed light on epilepsy pathogenesis, anti-seizure medication (ASM) resistance, and potential therapeutic targets. Gut dysbiosis is associated with inflammation, blood-brain barrier...

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PMID: 33140419
DOI: 10.1111/epi.16744

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