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Repeated Glucose Spikes and Insulin Resistance Synergistically Increase Endothelial Function Vulnerability to High Glucose Levels through Redox Imbalance, and Bardoxolone Methyl (CDDO-Me) Ameliorates Endothelial Dysfunction

2021-07-26

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Glucose spikes (GSs) observed after a meal in metabolic syndrome have been reported to cause endothelial dysfunction. However, other insulin resistance-related factors can affect GS-induced endothelial dysfunction. To eliminate these confounding factors, we investigated the separate and combined effects of GSs and insulin resistance due to diet-induced obesity on...

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Literature Corpus work: 6e301b54-214d-5f66-9bf1-8716de0f1788
DOI: 10.21203/rs.3.rs-731463/v1

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Repeated Glucose Spikes and Insulin Resistance Synergistically Increase Endothelial Function Vulnerability to High Glucose Levels through Redox Imbalance, and Bardoxolone Methyl (CDDO-Me) Ameliorates Endothelial DysfunctionDOI 10.21203/rs.3.rs-731463/v1Read

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