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New Insights into the Structural Requirements of Isatin-derived Pro-apoptotic Agents against Acute Myeloid Leukemia

2022-11-28

Abstract excerpt

Searching for bioactive compounds within the huge chemical space is like trying to find a needle in a haystack. Isatin is a unique natural compound which is endowed with different biopertinent activities specially in cancer therapy. Herein, we envisaged that adopting a hybrid strategy of isatin and α,β-unsaturated ketone would afford new chemical entities with strong chemotherapeutic potential. Of inter...

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Literature Corpus work
6e152878-e37a-5e44-b1f0-0f57abf075ac
DOI
10.20944/preprints202211.0509.v1
Open publication

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New Insights into the Structural Requirements of Isatin-derived Pro-apoptotic Agents against Acute Myeloid LeukemiaDOI 10.20944/preprints202211.0509.v1
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