Metabolomic Profiling of Dried Blood Spots for Breast Cancer Detection: A Multi-Classifier Validation Study in 2,734 Participants

Abstract excerpt

<h4>Background</h4> Breast cancer (BC) remains the most commonly diagnosed malignancy and the leading cause of cancer-related mortality among women worldwide. Although blood-based untar-geted metabolomics has emerged as a promising modality for detecting early-stage BC, its clinical translation has been bottlenecked by two unresolved issues: (i) the field has almost exclusively relied on serum or plasma, which re...

Topics

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• Breast Neoplasms
• Extracellular vesicles in disease
• Ferroptosis and cancer prognosis
• Genes, BRCA1
• Metabolomics
• Metabolomics and Mass Spectrometry Studies
• Mutation
• Nutritional Studies and Diet

Identifiers and source

Literature Corpus work

6de14cda-5f4f-5dd2-9e33-d02a90f187a5

DOI

10.64898/2026.04.24.26351695