Article

Circadian Rhythm Is Disrupted by ZNF704 in Breast Carcinogenesis

2020-01-09

Abstract excerpt

Copy number gain in chromosome 8q21 is considered as the prototype of genetic abnormalities associated with development of breast cancer, yet the oncogenic potential underlying this amplicon in breast carcinogenesis remains to be delineated. We report here that ZNF704 , a gene mapped to 8q21, is recurrently amplified in various malignancies including breast cancer. We found that ZNF704 acts as transcription repre...

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Literature Corpus work: 6cd00554-e707-51cb-9eaa-6951e38e89ec
DOI: 10.1101/2020.01.09.900548

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