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The immunoglobulin A isotype of the Arabian camel ( <i>Camelus dromedarius</i> ) preserves the dualistic structure of unconventional single-domain and canonical heavy chains

2023-09-06

Abstract excerpt

Evolutionary processes of adaptive immunity in Camelidae and some cartilaginous fishes resulted in the concurrent expression of classic heavy-light chain heterotetrameric antibodies together with unconventional heavy chain-only homodimeric antibodies of the IgG class. Heavy chain-only IgG bears a single variable domain and lacks the constant heavy (C H ) γ1 domain required for the covalent pairing with the light...

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Literature Corpus work
6c7a95fa-5ba9-5ebe-acda-59bd7c8d9ea4
DOI
10.1101/2023.09.04.556198
Open publication

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The immunoglobulin A isotype of the Arabian camel ( <i>Camelus dromedarius</i> ) preserves the dualistic structure of unconventional single-domain and canonical heavy chainsDOI 10.1101/2023.09.04.556198
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