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Variable fragments of heavy chain antibodies (VHHs): a new magic bullet molecule of medicine?

14 Jun 2012

Abstract excerpt

Serum of animals belonging to the Camelidae family (camels and llamas) contains fully active antibodies that are naturally devoid of light chains. Variable domains derived from heavy chain antibodies (hcAb) called VHHs or nanobodies™ can bind antigens as effectively as full-length antibodies and are easy to clone and express. Because of their potential, VHHs are being intensively studied as potential therapeutic,...

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Galectins and Cancer Biology
Glycosylation and Glycoproteins Research
Monoclonal and Polyclonal Antibodies Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22706121
DOI: 10.5604/17322693.1000334

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