Article

Beyond Wolfram Syndrome 1: The WFS1 Gene’s Role in Alzheimer’s Disease and Psychiatric Sleep Disorders

2024-09-30

Abstract excerpt

The WFS1 gene was first identified in Wolfram Syndrome 1 (WS1), a rare autosomal recessive genetic disorder characterized by severe and progressive neurodegenerative changes. WFS1's role in various cellular mechanisms, particularly in calcium homeostasis and the modulation of endoplasmic reticulum (ER) stress, suggests its potential involvement in the pathogenesis of Alzheimer's disease (AD) and psychiat...

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Literature Corpus work: 6c68f1ac-078f-5c10-9f3e-7355dfb451fb
DOI: 10.20944/preprints202409.2402.v1

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