Successful use of lanadelumab in an elderly patient with type II hereditary angioedema

Abstract excerpt

Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurring episodes of subcutaneous and/or submucosal edema without urticaria due to an excess of bradykinin (1, 2). HAE is classified into 2 main types (1). Type I HAE is caused by deficiency of C1 esterase inhibitor, accounting for 85% of cases (1). Type II HAE occurs in only 15% of cases and is marked by normal to elevated levels of C1 ester...

Topics

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• Angioedema
• Angioedemas, Hereditary
• Antibodies, Monoclonal, Humanized
• Coagulation, Bradykinin, Polyphosphates, and Angioedema
• Complement C1 Inhibitor Protein
• Factor XII
• Mutation
• Treatment Outcome

Identifiers and source

Literature Corpus work

6c3bee1e-d6e9-5a12-9fff-71a634f0fc99

DOI

10.22541/au.163352939.93914485/v1