Initial Experience of Long-Term Prophylaxis with Lanadelumab for Hereditary Angioedema in China: a Clinical Observation of Four patients.

Abstract excerpt

<title>Abstract</title> <p>Background Hereditary angioedema (HAE) is a rare genetic disorder caused by a deficiency or dysfunction of C1 esterase inhibitor (C1-INH), which leads to recurrent episodes of bradykininmediated edema. Lanadelumab is a plasma kallikrein inhibitor that is the only first line therapy for long term prophylaxis (LTP) of HAE attacks in China since 2021. Objectives To observe the clincial e...

Topics

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• Angioedema
• Angioedemas, Hereditary
• Coagulation, Bradykinin, Polyphosphates, and Angioedema
• Complement C1 Inhibitor Protein
• Diagnosis, Differential
• Disease Management
• Mutation
• Urticaria

Identifiers and source

Literature Corpus work

77d85d20-5777-5a4c-81ee-9d32c1550989

DOI

10.21203/rs.3.rs-3821482/v1