Article

<i>DPYD</i>genetic polymorphisms in non-European patients with severe fluoropyrimidine-related toxicity: A systematic review

2023-12-11

Abstract excerpt

<h4>Background</h4> Pre-treatment DPYD screening is mandated in the UK and EU to reduce the risk of severe and potentially fatal fluoropyrimidine-related toxicity. Four DPYD gene variants which are more prominently found in Europeans are tested. <h4>Methods</h4> Our systematic review in patients of non-European ancestry followed PRISMA guidelines to identify relevant articles up to April 2023. Published in silico...

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Literature Corpus work: 6c265c30-d520-56cb-b1f4-6c76836d344c
DOI: 10.1101/2023.12.11.23299813

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