Article

Phospho heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection

2022-10-14

Abstract excerpt

Global high-throughput phosphoproteomic profiling is increasingly being applied to cancer specimens to identify the oncogenic signaling cascades responsible for promoting disease initiation and disease progression; pathways that are often invisible to genomics analysis. Hence, phosphoproteomic profiling has enormous potential to inform and improve individualized anti-cancer treatment strategies. However, to achiev...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6bdf7d73-431e-5907-9379-4bd3ff3ac35b
DOI: 10.21203/rs.3.rs-2152430/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Phospho heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selectionDOI 10.21203/rs.3.rs-2152430/v1Read

High-Throughput Global Phosphoproteomic Profiling Using Phospho Heavy-Labeled-Spiketide FAIMS Stepped-CV DDA (pHASED)Semantic proximity Read

TOPAS: phosphoproteome data analysis and decision support platform for molecular tumor boardsSemantic proximity Read

Proteomics and Phosphoprotoemic Measurements Enhance Ability to Predict Ex Vivo Drug Response in AMLSemantic proximity Read

Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AMLSemantic proximity Read

Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.Semantic proximity Read

Multiplexed Data-Independent Acquisition (mDIA) to Profile Extracellular Vesicle ProteomesSemantic proximity Read

Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines.Semantic proximity Read

Phosphoproteomics of MAPK inhibition in BRAF-mutated cells and a role for the lethal synergism of dual BRAF and CK2 inhibition.Semantic proximity Read

Multiplexed Data-Independent Acquisition (mDIA) to Profile Extracellular Vesicle Proteomes.Semantic proximity Read

Utilizing proteomics and phosphoproteomics to predict <i>ex vivo</i> drug sensitivity across genetically diverse AML patientsSemantic proximity Read

Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategiesSemantic proximity Read

Sensitive, High-Throughput HLA-I and HLA-II Immunopeptidomics Using Parallel Accumulation-Serial Fragmentation Mass SpectrometrySemantic proximity Read