Article

Proteomics and Phosphoprotoemic Measurements Enhance Ability to Predict Ex Vivo Drug Response in AML

2022-01-26

Abstract excerpt

Acute Myeloid Leukemia (AML) affects 20,000 patients in the US annually with a five-year survival rate of approximately 25%. One reason for the low survival rate is the high prevalence of clonal evolution that gives rise to heterogeneous sub-populations of leukemic cells with diverse mutation spectra, which eventually leads to disease relapse. This genetic heterogeneity drives the activation of complex signaling p...

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Literature Corpus work: ae80a7a0-0989-524e-95e8-fc895a25a83b
DOI: 10.21203/rs.3.rs-1277906/v1

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