Article

cAMP Agonist Forskolin Disrupts Mitochondrial Metabolism and Induces Senescence in Human Mesenchymal Cells

2021-06-25

Abstract excerpt

<title>Abstract</title> <p><bold>Backgroud: </bold>Adult-derived mesenchymal stem cells (MSCs) can be used in therapies for the treatment of various diseases. However, MSCs derived from aging tissues or long-term MSC cultures could have diminished therapeutic effects compared with MSCs derived from younger tissues, but the underlying mechanism has not been completely established. Dysfunction of energy metabolism...

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Literature Corpus work: 6b4b28eb-e2f6-53cf-b663-2594587f8c28
DOI: 10.21203/rs.3.rs-634834/v1

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