Intravenous Followed by Oral Varespladib as Late Adjunctive Therapy for Snakebite: a Phase II Randomized Clinical Trial

Abstract excerpt

<h4>Background</h4> Snakebite envenoming causes an estimated 138,000 deaths and more than 400,000 cases of permanent disability each year, disproportionately affecting low-resource regions. Antivenom is the only treatment but requires intravenous administration. We evaluated intravenous followed by oral varespladib as adjunctive therapy to antivenom in hospitalized patients with snakebite envenoming. <h4>Methods...

Topics

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• Advanced biosensing and bioanalysis techniques
• Africa South of the Sahara
• Biochemical and Structural Characterization
• Cross Reactions
• Genetic Variation
• Monoclonal and Polyclonal Antibodies Research
• Snakes
• Toxin Mechanisms and Immunotoxins

Identifiers and source

Literature Corpus work

6b323459-098e-5f10-ade4-b39516ae7545

DOI

10.64898/2026.06.26.26356695