Article

Bioinformatic design of venom toxin-specific antivenom to improve the treatment of snakebite in Africa

2013-01-01

Abstract excerpt

Antivenom is the only effective treatment against the systemic effects of snakebite and is currently developed by a century-old immunisation protocol that aims to generate IgGs capable of binding and neutralizing most (if not all) of the venom toxins. However, snake venoms comprise more than a hundred proteins and peptides that exhibit a significant diversity in terms of isoform complexity, toxicity and immunogeni...

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Literature Corpus work: b50d3782-f8b4-5bc1-b6de-c1f69998f145
DOI: 10.17638/00016453

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