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Article

H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum

1 Apr 2021

Abstract excerpt

BACKGROUND: The Plasmodium sexual gametocyte stages are the only transmissible form of the malaria parasite and are thus responsible for the continued transmission of the disease. Gametocytes undergo extensive functional and morphological changes from commitment to maturity, directed by an equally extensive control program. However, the processes that drive the differentiation and development of the gametocyte...

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PMID: 33794978
DOI: 10.1186/s13072-021-00393-9

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