Article

Pandemic Risk Assessment for a Swine Influenza A Virus in Comparative Human Substrates

2024-02-25

Abstract excerpt

Swine influenza A viruses pose a public health concern as novel and circulating strains occasionally spill over into human hosts, with the potential to cause disease. Crucial to preempting these events is the use of a threat assessment framework for human populations. However, established guidelines do not specify what animal models or in vitro substrates should be used. We completed an assessment of a contempora...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6b0183b2-d51d-5586-8375-5c742ef0c673
DOI: 10.1101/2024.02.24.581872

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pandemic Risk Assessment for a Swine Influenza A Virus in Comparative Human SubstratesDOI 10.1101/2024.02.24.581872Read

Human H7N9 Influenza A Viruses Replicate in Swine Respiratory Tissue ExplantsSemantic proximity Read

Swine as a Model for Influenza A Virus Infection and ImmunitySemantic proximity Read

2018-2019 human seasonal H3N2 influenza A virus spillovers into swine with demonstrated virus transmission in pigs were not sustained in the pig populationSemantic proximity Read

Tissue Tropism of Swine Influenza Viruses and Reassortants in Ex Vivo Cultures of the Human Respiratory Tract and ConjunctivaSemantic proximity Read

Pathogenesis and Transmission of Genetically Diverse Swine-Origin H3N2 Variant Influenza A Viruses from Multiple Lineages Isolated in the United States, 2011–2016Semantic proximity Read

Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using ex vivo and in vitro cultures of the human respiratory tract.Semantic proximity Read

Transmission and pathologic findings of divergent human seasonal H1N1pdm09 influenza A viruses following spillover into pigs in the United StatesSemantic proximity Read

Porcine Airway Organoid-Derived Well-Differentiated Epithelial Cultures as a Tool for Characterization of Swine Influenza a Virus StrainsSemantic proximity Read

Population dynamics of cocirculating swine influenza <scp>A</scp> viruses in the <scp>U</scp>nited <scp>S</scp>tates from 2009 to 2012Semantic proximity Read

Evaluation of the human adaptation of influenza A/H7N9 virus in PB2 protein using human and swine respiratory tract explant cultures.Semantic proximity Read

Potential pandemic risk of circulating swine H1N2 influenza virusesSemantic proximity Read

Human organoid systems reveal <i>in vitro</i> correlates of fitness for SARS-CoV-2 B.1.1.7Semantic proximity Read