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Glycerol-3-Phosphate Dehydrogenase 1-Like serves as a tumor suppressor in colorectal cancer through ATF3-mediated ferroptosis

2025-08-27

Abstract excerpt

<title>Abstract</title> <p>Colorectal cancer (CRC) continues to be a prevalent malignancy, posing a significant risk to human health. The involvement of Glycerol-3-phosphate dehydrogenase 1-like (GPD1L) in CRC development was suggested by our analysis of clinical samples. However, the role of GPD1L in CRC remains unclear. This study seeks to elucidate the clinical relevance, biological function, and potential mol...

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Literature Corpus work
6ace52d6-fd2b-518a-9767-fa69642c32bb
DOI
10.21203/rs.3.rs-7120750/v1
Open publication

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